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Beyond the Basics: Why We Upgraded Our Best-Selling Argireline Solution

Jan 27,2026 | allaboutalicia

For years, our community has loved our Argireline Solution. It was simple, honest, and effective - much like the "Single-Active" approach made famous by brands like The Ordinary.  It did one thing, and it did well: it targeted espression lines.

But skincare science doesn't stand still, and neither do we.

Today, we are thrilled to unveil our New & Improved Multi-Peptide Complex.  We've moved from a "Single Instrument" to a "Full Orchestra".  Here is why we made the change and what it means for your skin.

The Evolution: From "Relaxing" to "Rebuilding"

Our original formula focused solely on Acetyl Hexapeptide-8.  This is a brilliant ingredient that works like a "topical botox" to relax the facial muscles that cause squint lines and forehead wrinkles.

However, aging isn't just about muscle movement.  It's about collagen loss, oxidation, and skin sagging.  To truly transform the skin, we needed more "players" on the field.

What's Inside the New "Gold Standard" Formula?

1. The Dynamic Duo - Hexapeptide-8 + Palmitoyl Pentapeptide-4

While the Six-Peptides relaxes the surface, we've added Palmitoyl Pentapeptide-4 (often called the "Collagen Fragment") to rebuild from within.  It signals your skin to produce more Collagen and Elastin.

  • The Result: You aren't just hiding wrinkles; you are actively firming the skin structure.

2. The Firming Specialist: Dipalmitoyl Hydroxyproline (DPHP)

This is our "secret weapon" found in ultra-luxury creams.  DPHP is a plant-derived carrier of Hydroxyproline (a key component of collagen).  It acts as a firming agent that helps "shrink-wrap" the skin, providing a lifted appearance that a simple water-based serum can't achieve.

3. The Glow & Shield: Glutathione + Carnosine

Anti-aging without anti-oxidation is a losing battle.

  • Glutathione: The master antioxidant.  It targets the "dullness" and yellowing that comes with age.
  • Carnosine: An anti-glycation hero.  It prevents sugar molecules from "caramelizing" your collagen, keeping your skin's support system flexible and bouncy.

4. The "Skin Comfort" Matrix: Betaine & Panthenol

We've replaced a basic water base with a soothing blend of Aloe Vera Juice, Betaine and Panthenol (Pro-Vitamin B5).  This ensures that while the high-potency actives work, your skin barrier remains calm, hydrated, and plump.

Why is this "Better" than the old formula?

  1. 360 degree Approach: We now target wrinkles from three angles: Muscle relaxation, Collagen synthesis, and Glycation protection.
  2. Superior Texture: Unlike thin, watery serums, our new Thickened Serum texture stays on the skin longer, ensuring better penetration of the active peptides.
  3. Visible Brightness: With the addition of Glutathione and Licorice Root (Dipotassium Glycyrrhizinate), you'll notice a "lit-from-within" glow that peptides alone cannot provide.

The Ultimate Youth-Preserving Ritual: How to Use the New Argireline Solution

To get the most out of our new "Gold Standard" formula, layering is key.  Here is the recommended routine featuring our Every Day Collection to ensure your skin is clean, hydrated, and ready to absorb every drop of peptide power.

Step 1: The Double Cleanse (Optional but Recommended)

Start with a blank canvas.

  • Dissolve: Use the Every Day Makeup Remover to lift away sunblock, makeup, and pollutants.
  • Purify: Follow up with the Every Day Face Wash.  A clean face ensures the large peptide molecules in our serum can penetrate deeper without being blocked by oils. 

Step 2: Hydrate & Prep (The Water Collection)

Peptides love a damp environment.  Before applying your serum, mist your face with your choice from Water Collection (like our antioxidant-rich Pomegranate Water) or swipe with the Every Day Toner.

3. The Treatment (Argireline Solution - Face & Neck)

  • Apply 5-6 drops (a slightly larger amount) of the Argireline Solution.
  • The Face: Focus on "movement" wrinkles - forehead and crow's feet.
  • The Neck: Use upward strokes from the collarbone toward the jawline.  This "lifting" motion helps the DPHP and peptides target the "necklace lines" and vertical bands on the neck.  Don't forget the decollete. where sun damage often causes fine, crepey lines 

Step 4: Target the Eyes

Next, apply the Every Day Eye Gel.  While the Argireline relaxes the muscles, the m-Tranexamic Acid and Vitamin B3 in our eye gel work to brighten dark circles and reduce puffiness.

Step 5: Seal, Protect & Firm

Finish your ritual with the Every Day Face Gel.  This "seals" the peptides inside.  The Rosehip and Sea Buckthorn oils in the Face Gel provide the essential fatty acids needed to strengthen the skin barrier, while the Niacinamide complements the brightening power of the Glutathione in your serum.  Don't forget the neck!

Frequently Asked Questions: Everything You Need to Know

Q: How soon will I see results?

A: You will notice an immediate "silky" and hydrated feel thanks to the Betaine and B5.  For the anti-wrinkle effects, most users see a visible softening of expression lines within 15-30 days of consistent use.  For deeper firming of the neck and jawline (thanks to the DPHP), allow 6-8 weeks for your skin to rebuild its collagen support. 

Q: Can I use this with Vitamin C or Salicylic Acid?

A: No for Vitamin C and yes for Salycylic Acid.  You may refer to my blog - Morning C, Night A: The Ultimate Guide to Glowing Skin with All About Alicia’s Elixir Collectiong-skin-with-all-about-alicia%E2%80%99s-elixir-collection

Q: Why does the new formula feel thicker than the old one?

A: Great question!  Our original formula was water-based.  The new "Gold Standard" version is a thickened serum.  This texture is intentional  - it creates a "film" on the skin that allows the Peptides and Glutathione to stay in contact with your skin longer, ensuring better absorptionand a more luxurious feel.

Q: Is it safe for sensitive skin?

A: Absolutely. We've included Aloe Vera and Dipotassium Glycyrrhizinate (Licorice Root) specifically to calm the skin.  Unlike "Acid" treatments, Peptides are very gentle and generally non-irritating, making them perfect for sensitive or thinning skin.

Q:  My skin is very dry. Is this enough moisture?

A: This serum is a high-potency treatment.  While it contains Hyaluronic Acid, we always recommend sealing it in with our Every Day Face Gel.  For mature skin, the combination of "Water-based Actives" (the serum) followed by "Lipid-rich Protection" (the gel) is the secret to a 24-hour glow.

Get our New & Improved Argireline Solution here